A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery

Abstract Background Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. We tested this hypothesis in a multi-center study. Methods The patients were included in two periods: a first control period (control gro...

Full description

Bibliographic Details
Main Authors: Luiz Marcelo Sá Malbouisson, João Manoel Silva, Maria José Carvalho Carmona, Marcel Rezende Lopes, Murilo Santucci Assunção, Jorge Luís dos Santos Valiatti, Claudia Marques Simões, José Otavio Costa Auler
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Anesthesiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12871-017-0356-9