Linearization of genome sequence graphs revisited

Summary: The need to include the genetic variation within a population into a reference genome led to the concept of a genome sequence graph. Nodes of such a graph are labeled with DNA sequences occurring in represented genomes. Due to double-stranded nature of DNA, each node may be oriented in one...

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Bibliographic Details
Main Authors: Anna Lisiecka, Norbert Dojer
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007239