Preparation of Microparticles Capable of Glucose-Induced Insulin Release under Physiological Conditions

Preparation of Microparticles Capable of Glucose-Induced Insulin Release under Physiological Conditions

Hydrogen peroxide (H2O2)-sensitive layer-by-layer films were prepared based on combining phenyl boronic acid (PBA)-modified poly(allylamine) (PAH) with shikimic acid (SA)-modified-PAH through boronate ester bonds. These PBA-PAH/SA-PAH multilayer films could be prepared in aqueous solutions at pH 7.4...

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Bibliographic Details
Main Authors: Kentaro Yoshida, Kazuma Awaji, Seira Shimizu, Miku Iwasaki, Yuki Oide, Megumi Ito, Takenori Dairaku, Tetsuya Ono, Yoshitomo Kashiwagi, Katsuhiko Sato
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Polymers
Subjects:
phenyl boronic acid
hydrogen peroxide
drug delivery system
insulin
LbL film
glucose response
Online Access:http://www.mdpi.com/2073-4360/10/10/1164

Internet

http://www.mdpi.com/2073-4360/10/10/1164

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