Engineered microbial biosensors based on bacterial two-component systems as synthetic biotechnology platforms in bioremediation and biorefinery

Abstract Two-component regulatory systems (TCRSs) mediate cellular response by coupling sensing and regulatory mechanisms. TCRSs are comprised of a histidine kinase (HK), which serves as a sensor, and a response regulator, which regulates expression of the effector gene after being phosphorylated by...

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Bibliographic Details
Main Authors: Sambandam Ravikumar, Mary Grace Baylon, Si Jae Park, Jong-il Choi
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0675-z