Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies

Renata Curciarello,1,2 Toni Sobande,2 Samantha Jones,2 Paolo Giuffrida,2,3 Antonio Di Sabatino,3 Guillermo H Docena,1 Thomas T MacDonald,2 Klaartje Kok2,4 1Instituto de Estudios Inmunológicos y Fisiopatológicos IIFP-CONICET, Universidad Nacional de La Plata, La Plata, Buenos Ai...

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Bibliographic Details
Main Authors: Curciarello R, Sobande T, Jones S, Giuffrida P, Di Sabatino A, Docena GH, MacDonald TT, Kok K
Format: Article
Language:English
Published: Dove Medical Press 2020-05-01
Series:Journal of Inflammation Research
Subjects:
Online Access:https://www.dovepress.com/human-neutrophil-elastase-proteolytic-activity-in-ulcerative-colitis-f-peer-reviewed-article-JIR