Estimation and discrimination of stochastic biochemical circuits from time-lapse microscopy data.

The ability of systems and synthetic biologists to observe the dynamics of cellular behavior is hampered by the limitations of the sensors, such as fluorescent proteins, available for use in time-lapse microscopy. In this paper, we propose a generalized solution to the problem of estimating the stat...

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Bibliographic Details
Main Authors: David Thorsley, Eric Klavins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3491022?pdf=render