A protocol for preparation of chromosome spread and processing for transmission electron microscopy

<p>Transmission electron microscopic (TEM) observation of human chromosome ultrastructure may provide useful information on various abnormalities. Due to the difficulties in detaching metaphase chromosome spreads from the glass slide, this approach has been restricted. We introduce a simplifie...

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Bibliographic Details
Main Authors: Tatsuo Oguro, Mohammad Ghazizadeh
Format: Article
Language:English
Published: American Journal of Experimental and Clinical Research 2015-04-01
Series:American Journal of Experimental and Clinical Research
Subjects:
Online Access:http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/53