Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection

Summary: Sex differences in autoimmunity and infection suggest that a better understanding of molecular sex differences will improve the diagnosis and treatment of immune-related disease. We identified 144 differentially expressed genes, referred to as immune sex expression signature (iSEXS), betwee...

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Bibliographic Details
Main Authors: Erika Bongen, Haley Lucian, Avani Khatri, Gabriela K. Fragiadakis, Zachary B. Bjornson, Garry P. Nolan, Paul J. Utz, Purvesh Khatri
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313191