Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells

Abstract Background The CDKN2A/B locus contains crucial tumor suppressors and a lncRNA gene ANRIL. However, the mechanisms that coordinately regulate their expression levels are not clear. Methods Novel RNAs transcribed from the CDKN2A gene were screened by CDKN2A-specific RNA capture deep-sequencin...

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Bibliographic Details
Main Authors: Wanru Ma, Juanli Qiao, Jing Zhou, Liankun Gu, Dajun Deng
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Molecular Cancer
Subjects:
P16
Online Access:http://link.springer.com/article/10.1186/s12943-020-01150-4