Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells
Abstract Background The CDKN2A/B locus contains crucial tumor suppressors and a lncRNA gene ANRIL. However, the mechanisms that coordinately regulate their expression levels are not clear. Methods Novel RNAs transcribed from the CDKN2A gene were screened by CDKN2A-specific RNA capture deep-sequencin...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-020-01150-4 |