Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging

<p>Abstract</p> <p>Background</p> <p>The cytokines interleukin-1 and tumor necrosis factor (TNF), and the cytokine blocker interleukin-1 receptor antagonist, all have been demonstrated to enter the cerebrospinal fluid (CSF) following peripheral administration. Recent re...

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Bibliographic Details
Main Authors: Chen Xiaoyuan, Chen Kai, Tobinick Edward L
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/28