SSPH I, a Novel Anti-Cancer Saponin, Inhibits Autophagy and Induces Apoptosis via ROS Accumulation and ERK1/2 Signaling Pathway in Hepatocellular Carcinoma Cells

Jin-ling Zhou,1,* Xiu-ying Huang,2,* Han-chen Qiu,3 Ri-zhi Gan,1 Huan Zhou,1 Hong-qing Zhu,1 Xuan-xuan Zhang,1 Guo-dong Lu,4 Gang Liang1 1School of Pharmacy, Guangxi Medical University, Nanning, People’s Republic of China; 2Liuzhou Employment Service Centre for the Disabled, Liuzhou, Peopl...

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Bibliographic Details
Main Authors: Zhou J, Huang X, Qiu H, Gan R, Zhou H, Zhu H, Zhang X, Lu G, Liang G
Format: Article
Language:English
Published: Dove Medical Press 2020-06-01
Series:OncoTargets and Therapy
Subjects:
ros
Online Access:https://www.dovepress.com/ssph-i-a-novel-anti-cancer-saponin-inhibits-autophagy-and-induces-apop-peer-reviewed-article-OTT