A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy

Abstract Colon cancer induces a state of mucosal dysbiosis with associated niche specific changes in the gut microbiota. However, the key metabolic functions of these bacteria remain unclear. We performed a prospective observational study in patients undergoing elective surgery for colon cancer with...

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Bibliographic Details
Main Authors: James Kinross, Reza Mirnezami, James Alexander, Richard Brown, Alasdair Scott, Dieter Galea, Kirill Veselkov, Rob Goldin, Ara Darzi, Jeremy Nicholson, Julian R. Marchesi
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08150-3