Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells

NDRG1 (N-myc downstream regulated gene-1) is a metastasis suppressor that is down-regulated in prostate cancer. NDRG1 phosphorylation is associated with inhibition of metastasis and Western blots indicate two bands at ~41 and ~46 kDa. Previous investigations by other...

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Bibliographic Details
Main Authors: Mohammad K. Ghalayini, Qihan Dong, Des R. Richardson, Stephen J. Assinder
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-06-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/033/e042/bsr033e042.htm