P2X7 Receptor Deficiency Ameliorates STZ-induced Cardiac Damage and Remodeling Through PKCβ and ERK

P2X7 Receptor Deficiency Ameliorates STZ-induced Cardiac Damage and Remodeling Through PKCβ and ERK

Diabetic cardiomyopathy (DCM) is a complication of diabetes mellitus which result in cardiac remodeling and subsequent heart failure. However, the role of P2X7 receptor (P2X7R) in DCM has yet to be elucidated. The principal objective of this study was to investigate whether P2X7R participates in the...

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Bibliographic Details
Main Authors: Shanjun Huang, Weiqi Wang, Li Li, Ting Wang, Yihan Zhao, Ya Lin, Weijian Huang, Yonghua Wang, Zhouqing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
diabetic cardiomyopathy
P2X7 receptor
cardiac remodeling
PKCβ
ERK
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.692028/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.692028/full

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