The Developmental Phenotype of the Great Toe in Fibrodysplasia Ossificans Progressiva

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder in which extensive heterotopic ossification (HO) begins to form during early childhood and progresses throughout life. Although HO does not occur during embryonic development, children who carry the ACVR1R206H mutation that cause...

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Bibliographic Details
Main Authors: O. Will Towler, Frederick S. Kaplan, Eileen M. Shore
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FOP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.612853/full