MicroRNA-200b is downregulated in colon cancer budding cells.

The microRNA-200 (miR-200) family acts as a major suppressor of epithelial-mesenchymal transition (EMT). Impaired miR-200 expression may lead to EMT initiation and eventually cancer dissemination. The presence of tumor budding cells (TBC) is associated with metastasis and poor prognosis, and molecul...

Full description

Bibliographic Details
Main Authors: Kirsten Nguyen Knudsen, Jan Lindebjerg, Boye Schnack Nielsen, Torben Frøstrup Hansen, Flemming Brandt Sørensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5446202?pdf=render