The two-component system CpxR/A represses the expression of Salmonella virulence genes by affecting the stability of the transcriptional regulator HilD

Salmonella enterica can cause intestinal or systemic infections in humans and animals mainly by the presence of pathogenicity islands SPI-1 and SPI-2, containing 39 and 44 genes, respectively. The AraC-like regulator HilD positively controls the expression of the SPI-1 genes, as well as many other S...

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Bibliographic Details
Main Authors: Miguel Ángel De la Cruz, Deyanira ePérez-Morales, Irene Jaqueline Palacios, Marcos eFernández-Mora, Edmundo eCalva, Victor H Bustamante
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Lon
SPI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00807/full