Methotrexate use and NAD+/NADH metabolism in psoriatic keratinocytes

Methotrexate use and NAD+/NADH metabolism in psoriatic keratinocytes

Methotrexate inhibits tetrahydrofolic acid production and influences mitochondrial oxygen uptake and activity of several enzymes in the respiratory chain reactions, which utilize nicotinamide adenine dinucleotide-linked (NAD-linked) substrates. Hyperproliferation of keratinocytes in psoriasis requir...

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Bibliographic Details
Main Authors: Agata Liszewska, Ewa Robak, Małgorzata Bernacka, Jarosław Bogaczewicz, Anna Woźniacka
Format: Article
Language:English
Published: Termedia Publishing House 2020-03-01
Series:Advances in Dermatology and Allergology
Subjects:
methotrexate
psoriasis
nicotinamide-adenine dinucleotide
spectrophotometry
mitochondria
Online Access:https://www.termedia.pl/Methotrexate-use-and-NAD-NADH-metabolism-r-nin-psoriatic-keratinocytes,7,40007,1,1.html

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https://www.termedia.pl/Methotrexate-use-and-NAD-NADH-metabolism-r-nin-psoriatic-keratinocytes,7,40007,1,1.html

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