The Integral Role of RNA in Stress Granule Formation and Function

Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein (RNP) assemblies whose primary function is to promote cell survival by condensing translationally stalled mRNAs, ribosomal components, translation initiation factors, and RNA-binding proteins (RBPs). While the pro...

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Bibliographic Details
Main Authors: Danae Campos-Melo, Zachary C. E. Hawley, Cristian A. Droppelmann, Michael J. Strong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RNA
RNP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.621779/full