Identification of aminosulfonylarylisoxazole as microRNA-31 regulators.

The discovery of small-molecule regulators of microRNAs remains challenging, but a few have been reported. Herein, we describe small-molecule inhibitors of miR-31, a tumor-associated microRNA (miRNA), identified by high-throughput screening using a cell-based reporter assay. Aminosulfonylarylisoxazo...

Full description

Bibliographic Details
Main Authors: Kyungtaek Im, Jiho Song, Young Taek Han, Seul Lee, Soowon Kang, Kwang Woo Hwang, Hyeyoung Min, Kyung Hoon Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5544221?pdf=render