Association between glucocorticoid receptor methylation and hippocampal subfields in major depressive disorder.

BACKGROUND: DNA methylation in the promoter region of the glucocorticoid receptor gene (NR3C1) is closely associated with childhood adversity and suicide. However, few studies have examined NR3C1 methylation in relation to major depressive disorder (MDD) and hippocampal subfield volumes. We investig...

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Main Authors: Kyoung-Sae Na, Hun Soo Chang, Eunsoo Won, Kyu-Man Han, Sunyoung Choi, Woo Suk Tae, Ho-Kyoung Yoon, Yong-Ku Kim, Sook-Haeng Joe, In-Kwa Jung, Min-Soo Lee, Byung-Joo Ham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897456?pdf=render