Future Preventive Gene Therapy of Polygenic Diseases from a Population Genetics Perspective

Future Preventive Gene Therapy of Polygenic Diseases from a Population Genetics Perspective

With the accumulation of scientific knowledge of the genetic causes of common diseases and continuous advancement of gene-editing technologies, gene therapies to prevent polygenic diseases may soon become possible. This study endeavored to assess population genetics consequences of such therapies. C...

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Bibliographic Details
Main Author: Roman Teo Oliynyk
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
polygenic risk
polymorphism
heritability
polygenic disease
simulation
gene therapy
gene editing
stratification
lifetime risk
admixture
Online Access:https://www.mdpi.com/1422-0067/20/20/5013

Internet

https://www.mdpi.com/1422-0067/20/20/5013

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