Superior protective effects of febuxostat plus alpha-lipoic acid on renal ischemia/reperfusion-induced hepatorenal injury in rats

A complex cascade of pathological events including oxidative stress and inflammation is involved in ischemia/reperfusion (I/R)-induced local and remote organ injuries. This study was performed to evaluate the effects of febuxostat (FEB), a selective xanthine oxidase (XO) inhibitor, and alpha-lipoic...

Full description

Bibliographic Details
Main Authors: Mahmoud M Farag, Sally M Ahmed, Wessam F Elhadidy, Radwa M Rashad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=6;spage=1364;epage=1374;aulast=Farag