Topical application of PPADS inhibits complement activation and choroidal neovascularization in a model of age-related macular degeneration.

Topical application of PPADS inhibits complement activation and choroidal neovascularization in a model of age-related macular degeneration.

Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly. AMD patients have elevated levels of membrane attack complex (MAC) in their choroidal blood vessels and retinal pigment epithelium (RPE). MAC forms pores in cell membranes. Low levels of MAC result in an...

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Bibliographic Details
Main Authors: Kerstin Birke, Erion Lipo, Marco T Birke, Rajendra Kumar-Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793916?pdf=render

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http://europepmc.org/articles/PMC3793916?pdf=render

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