High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity

High-throughput and computational tools provide a new opportunity to calculate combined bioactivity of exposure to diverse chemicals acting through a common mechanism. We used high throughput in vitro bioactivity data and exposure predictions from the U.S. EPA’s Toxicity and Exposure Forecaster (Tox...

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Bibliographic Details
Main Authors: Susanna H. Wegner, Caroline L. Pinto, Caroline L. Ring, John F. Wambaugh
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019325474