Neuroadaptation in Nicotine Addiction: Update on the Sensitization-Homeostasis Model

The role of neuronal plasticity in supporting the addictive state has generated much research and some conceptual theories. One such theory, the sensitization-homeostasis (SH) model, postulates that nicotine suppresses craving circuits, and this triggers the development of homeostatic adaptations th...

Full description

Bibliographic Details
Main Authors: Jean King, Joseph R. DiFranza, Wei Huang
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Brain Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3425/2/4/523