Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K

Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K

Vectorial transport of organic cations (OCs) in renal proximal tubules is mediated by sequential action of human OC transporter 2 (hOCT2) and human multidrug and toxic extrusion protein 1 and 2K (hMATE1 and hMATE2K), expressed in the basolateral (hOCT2) and luminal (hMATE1 and hMATE2K) plasma membra...

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Bibliographic Details
Main Authors: Marta Kantauskaitė, Anna Hucke, Moritz Reike, Sara Ahmed Eltayeb, Chuyan Xiao, Vivien Barz, Giuliano Ciarimboli
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
organic cations
transport
kidneys
regulation
Online Access:https://www.mdpi.com/1422-0067/21/14/5157

Internet

https://www.mdpi.com/1422-0067/21/14/5157

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