Optimization of Enzymatic Synthesis of Betulinic Acid Amide in Organic Solvent by Response Surface Methodology (RSM)

Optimization of the lipase catalyzed enzymatic synthesis of betulinic acid amide in the presence of immobilized lipase, Novozym 435 from Candida antartica as a biocatalyst was studied. Response surface methodology (RSM) and 5-level-4-factor central-composite rotatable design (CCRD) were employed to...

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Bibliographic Details
Main Authors: Nurul Atikah Amin Yusof, Nursyamsyila Mat Hadzir, Siti Efliza Ashari, Nor Suhaila Mohamad Hanapi, Rossuriati Dol Hamid
Format: Article
Language:English
Published: Universitas Gadjah Mada 2019-08-01
Series:Indonesian Journal of Chemistry
Subjects:
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/34903