Functional Analysis of Genetic Variations in Surfactant Protein D in Mycobacterial Infection and Their Association With Tuberculosis

Surfactant proteins (SPs)-A and -D are C-type lectins of the collectin family and function in the clearance of infectious particles in the lungs. Some polymorphisms of SPs that give rise to amino acid changes have been found to affect their function. Several SP-A gene polymorphisms have been reporte...

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Bibliographic Details
Main Authors: Miao-Hsi Hsieh, Chih-Ying Ou, Wen-Yu Hsieh, Hui-Fang Kao, Shih-Wei Lee, Jiu-Yao Wang, Lawrence S. H. Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01543/full