Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32

Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32

Imidazo[1,2-<i>b</i>]pyridazine compounds are a new class of promising lead molecules to which we have incorporated polar nitro and amino moieties to increase the scope of their biological activity. Two of these substituted 3-nitro-6-amino-imidazo[1,2-<i>b</i>]pyridazine comp...

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Bibliographic Details
Main Authors: Rakesh Kumar Sharma, Manisha Singh, Khagendra Ghimeray, Pinky Juneja, Gagan Dev, Sridhar Pulavarthi, Sabbasani Rajasekhara Reddy, Ravi Shankar Akundi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
acetylcholinesterase
anticancer drugs
cell proliferation
cyclooxygenase
cytotoxicity
imidazopyridazine
Online Access:https://www.mdpi.com/1420-3049/26/17/5319

Internet

https://www.mdpi.com/1420-3049/26/17/5319

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