APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.

BACKGROUND:With the onset of prevention trials for individuals at high risk for Alzheimer disease, there is increasing need for accurate risk prediction to inform study design and enrollment, but available risk estimates are limited. We developed risk estimates for the incidence of mild cognitive im...

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Main Authors: Jing Qian, Frank J Wolters, Alexa Beiser, Mary Haan, M Arfan Ikram, Jason Karlawish, Jessica B Langbaum, John M Neuhaus, Eric M Reiman, J Scott Roberts, Sudha Seshadri, Pierre N Tariot, Beth McCarty Woods, Rebecca A Betensky, Deborah Blacker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC5360223?pdf=render