The thermal and storage stability of bovine haemoglobin by ultraviolet–visible and circular dichroism spectroscopies

The effects of temperature, pH and long-term storage on the secondary structure and conformation changes of bovine haemoglobin (bHb) were studied using circular dichroism (CD) and ultraviolet--visible (UV–vis) spectroscopies. Neural network software was used to deconvolute the CD data to obtain the...

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Bibliographic Details
Main Authors: Ruchir Bhomia, Vivek Trivedi, Nichola J. Coleman, John C. Mitchell
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177916300089