HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.

HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.

BACKGROUND: In chronic HIV infection, antiretroviral therapy-induced normalization of CD4(+) T cell counts (immune reconstitution [IR]) is associated with a decreased incidence of opportunistic diseases. However, some individuals remain at risk for opportunistic diseases despite prolonged normalizat...

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Bibliographic Details
Main Authors: Olivier Gasser, Florian K Bihl, Marcel Wolbers, Elisabetta Loggi, Ingrid Steffen, Hans H Hirsch, Huldrych F Günthard, Bruce D Walker, Christian Brander, Manuel Battegay, Christoph Hess, Swiss HIV Cohort Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1831733?pdf=render

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http://europepmc.org/articles/PMC1831733?pdf=render

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