Pre-silencing of genes involved in the electron transport chain (ETC) pathway is associated with responsiveness to abatacept in rheumatoid arthritis

Pre-silencing of genes involved in the electron transport chain (ETC) pathway is associated with responsiveness to abatacept in rheumatoid arthritis

Abstract Background In the current context of personalized medicine, one of the major challenges in the management of rheumatoid arthritis (RA) is to identify biomarkers that predict drug responsiveness. From the European APPRAISE trial, our main objective was to identify a gene expression profile a...

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Bibliographic Details
Main Authors: C. Derambure, G. Dzangue-Tchoupou, C. Berard, N. Vergne, M. Hiron, M. A. D’Agostino, P. Musette, O. Vittecoq, T. Lequerré
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Arthritis Research & Therapy
Subjects:
Biomarkers
Rheumatoid arthritis
Abatacept
Microarray
Abatacept response
Oxydative stress
Online Access:http://link.springer.com/article/10.1186/s13075-017-1319-8

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http://link.springer.com/article/10.1186/s13075-017-1319-8

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