Parallel Mapping of Antibiotic Resistance Alleles in Escherichia coli.

Chemical genomics expands our understanding of microbial tolerance to inhibitory chemicals, but its scope is often limited by the throughput of genome-scale library construction and genotype-phenotype mapping. Here we report a method for rapid, parallel, and deep characterization of the response to...

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Bibliographic Details
Main Authors: Sophie J Weiss, Thomas J Mansell, Pooneh Mortazavi, Rob Knight, Ryan T Gill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4714920?pdf=render