Conservation of the “Outside-in” Germination Pathway in Paraclostridium bifermentans

Clostridium difficile spore germination is initiated in response to certain bile acids and amino acids (e.g., glycine). Though the amino acid-recognizing germinant receptor is unknown, the bile acid germinant receptor is the germination-specific, subtilisin-like pseudoprotease, CspC. In C. difficile...

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Bibliographic Details
Main Authors: Disha Bhattacharjee, Joseph A. Sorg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
DPA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02487/full