CDA: combinatorial drug discovery using transcriptional response modules.

BACKGROUND: Anticancer therapies that target single signal transduction pathways often fail to prevent proliferation of cancer cells because of overlapping functions and cross-talk between different signaling pathways. Recent research has identified that balanced multi-component therapies might be m...

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Bibliographic Details
Main Authors: Ji-Hyun Lee, Dae Gyu Kim, Tae Jeong Bae, Kyoohyoung Rho, Ji-Tae Kim, Jong-Jun Lee, Yeongjun Jang, Byung Cheol Kim, Kyoung Mii Park, Sunghoon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3414439?pdf=render