Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose

Phospholipids are an important class of lipids that act as building blocks of biological cell membranes and participate in a variety of vital cellular functions including cell signaling. Previous studies have reported alterations in phosphatidylcholine (PC) and lysophosphatidylcholine (lysoPC) metab...

Full description

Bibliographic Details
Main Authors: Sudeepa Bhattacharyya, Lisa Pence, Ke Yan, Pritmohinder Gill, Chunqiao Luo, Lynda G. Letzig, Pippa M. Simpson, Gregory L. Kearns, Richard D. Beger, Laura P. James
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750016300609