DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

Abstract Background MeCP2 and MBD2 are members of a family of proteins that possess a domain that selectively binds 5-methylcytosine in a CpG context. Members of the family interact with other proteins to modulate DNA packing. Stretching of DNA–protein complexes in nanofluidic channels with a cross-...

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Bibliographic Details
Main Authors: Ming Liu, Saeid Movahed, Saroj Dangi, Hai Pan, Parminder Kaur, Stephanie M. Bilinovich, Edgar M. Faison, Gage O. Leighton, Hong Wang, David C. Williams, Robert Riehn
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
MeCP2
MBD2
DNA compaction
Online Access:http://link.springer.com/article/10.1186/s13072-020-00339-7

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http://link.springer.com/article/10.1186/s13072-020-00339-7

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