Vitamin D deficiency in the ApcPirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective

Human studies have shown that individuals with colon cancer tend to have lower serum 25-hydroxy-vitamin D3 [25(OH)D3] levels compared with healthy controls, but whether this link is causative, a result of the disease or an indicator of another factor altogether has yet to be demonstrated. In humans,...

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Bibliographic Details
Main Authors: Amy A. Irving, Elizabeth G. Duchow, Lori A. Plum, Hector F. DeLuca
Format: Article
Language:English
Published: The Company of Biologists 2018-03-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/3/dmm032300