Effects of Anti-IL-17 on Inflammation, Remodeling, and Oxidative Stress in an Experimental Model of Asthma Exacerbated by LPS

Effects of Anti-IL-17 on Inflammation, Remodeling, and Oxidative Stress in an Experimental Model of Asthma Exacerbated by LPS

Inflammation plays a central role in the development of asthma, which is considered an allergic disease with a classic Th2 inflammatory profile. However, cytokine IL-17 has been examined to better understand the pathophysiology of this disease. Severe asthmatic patients experience frequent exacerbat...

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Bibliographic Details
Main Authors: Leandro do Nascimento Camargo, Renato Fraga Righetti, Luciana Ritha de Cássia Rolim Barbosa Aristóteles, Tabata Maruyama dos Santos, Flávia Castro Ribas de Souza, Silvia Fukuzaki, Maysa Mariana Cruz, Maria Isabel Cardoso Alonso-Vale, Beatriz Mangueira Saraiva-Romanholo, Carla Máximo Prado, Mílton de Arruda Martins, Edna Aparecida Leick, Iolanda de Fátima Lopes Calvo Tibério
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
anti-IL-17
distal lung
asthma
inflammation
LPS-exacerbated
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01835/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01835/full

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