In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan.

In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan.

Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of action but a wide range of different responses depending on the patient. Explorin...

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Bibliographic Details
Main Authors: Guillem Jorba, Joaquim Aguirre-Plans, Valentin Junet, Cristina Segú-Vergés, José Luis Ruiz, Albert Pujol, Narcís Fernández-Fuentes, José Manuel Mas, Baldo Oliva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228926

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https://doi.org/10.1371/journal.pone.0228926

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