Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-Thiocyanatobenzoic Acid
Dehydroalanine exists natively in certain proteins and can also be chemically made from the protein cysteine. As a strong Michael acceptor, dehydroalanine in proteins has been explored to undergo reactions with different thiolate reagents for making close analogues of post-translational modification...
Main Authors: | Yuchen Qiao, Ge Yu, Sunshine Z. Leeuwon, Wenshe Ray Liu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/9/2619 |
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