Wenxin Keli for the Treatment of Arrhythmia—Systems Pharmacology and In Vivo Pharmacological Assessment

Wenxin Keli for the Treatment of Arrhythmia—Systems Pharmacology and In Vivo Pharmacological Assessment

This study employed a systems pharmacology approach to identify the active compounds and action mechanisms of Wenxin Keli for arrhythmia treatment. Sixty-eight components identified in vivo and in vitro by UPLC/Q-TOF-MS were considered the potential active components of Wenxin Keli. Network pharmaco...

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Bibliographic Details
Main Authors: Xiaofeng Li, Gang Tian, Liang Xu, Lili Sun, Rui Tao, Shaoqiang Zhang, Zidong Cong, Fangjun Deng, Jinhong Chen, Yang Yu, Wuxun Du, Hucheng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
Wenxin Keli
arrhythmia
active compounds
action mechanisms
systems phar macology
Ca2+ balance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.704622/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.704622/full

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