Modulation of SIV and HIV DNA Vaccine Immunity by Fas-FasL Signaling

Signaling through the Fas/Apo-1/CD95 death receptor is known to affect virus-specific cell-mediated immune (CMI) responses. We tested whether modulating the Fas-apoptotic pathway can enhance immune responses to DNA vaccination or lymphocytic choriomeningitis virus (LCMV) infection. Mice were elect...

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Bibliographic Details
Main Authors: Jiabin Yan, Juan Carlos Zapata, Charles David Pauza, Maria S. Salvato
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/3/1429