From influenza infection to anti-ADAMTS13 autoantibodies via cross-reactivity

From influenza infection to anti-ADAMTS13 autoantibodies via cross-reactivity

Autoantibodies (AAbs) against von Willebrand factor (vWF)-cleaving protease ADAMTS13 causally relate to thrombotic thrombocytopenic purpura (TTP). How anti-ADAMTS13 AAbs are generated is unknown. Starting from reports according to which influenza infection can trigger TTP by the production of ADAMTS...

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Bibliographic Details
Main Author: Kanduc Darja
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Infection International
Subjects:
influenza infection
adamts13
peptide sharing
autoantibodies
cross-reactivity
thrombotic thrombocytopenic purpura
Online Access:http://www.degruyter.com/view/j/ii.2019.7.issue-4/ii-2019-0002/ii-2019-0002.xml?format=INT

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http://www.degruyter.com/view/j/ii.2019.7.issue-4/ii-2019-0002/ii-2019-0002.xml?format=INT

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