Aristolochic Acid-Induced Autophagy Promotes Epithelial-to-Myofibroblast Transition in Human Renal Proximal Tubule Epithelial Cells

Autophagy plays an essential role in cellular homeostasis in kidney. Previous studies have found that aristolochic acid (AA) can induce autophagy of renal tubular epithelial cells and epithelial-to-myofibroblast transition (EMT). However, the relationship between AA-induced autophagy and EMT is uncl...

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Bibliographic Details
Main Authors: Yu-Lin Man, Hong-Liang Rui, Yi-Pu Chen, Guo-qin Wang, Li-Jun Sun, Hong Cheng
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2017/9596256