Evolutionary insights into heart regeneration

Abstract Some lower vertebrates such as zebrafish and axolotl have incredible cardiac regenerative potential while mammals have very limited ones. Comparative studies among species have revealed that cardiomyocyte polyploidy, endothermy, and injury-induced activation of certain transcriptional facto...

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Bibliographic Details
Main Author: Jing-Wei Xiong
Format: Article
Language:English
Published: SpringerOpen 2020-12-01
Series:Cell Regeneration
Online Access:https://doi.org/10.1186/s13619-020-00069-x