Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease.

BACKGROUND: Serine proteases promote inflammation and tissue remodeling by activating proteinase-activated receptors, urokinase, metalloproteinases and angiotensin. In the present study, 4-(2-Aminoethyl) benzenesulfonyl fluoride (AEBSF) a serine protease inhibitor was evaluated for prophylactic and...

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Bibliographic Details
Main Authors: Sanjay Saw, Sagar Laxman Kale, Naveen Arora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3400607?pdf=render