A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase

Viral RNA helicases are involved in duplex unwinding during the RNA replication of the virus. It is suggested that these helicases represent very promising antiviral targets. Viruses of the flaviviridae family are the causative agents of many common and devastating diseases, including hepatitis, yel...

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Bibliographic Details
Main Authors: Dimitrios Vlachakis, Vassiliki Lila Koumandou, Sophia Kossida
Format: Article
Language:English
Published: PeerJ Inc. 2013-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/74.pdf